Professor Stefan T. Arold

Principal Investigator





Professor of Bioscience, at KAUST since 2013, PI of the Structural Biology & Engineering (StruBE) group. Prof. Arold’s research is dedicated to elucidating the molecular basis of the function and (de)regulation of proteins central to cellular key signaling networks. His investigations are based on an integrated structural biology approach that combines functional and structural data from multiple sources (small angle X-ray scattering, X-ray crystallography, NMR, computational methods, biochemistry, high-throughput ligand binding assays and functional analyses). Some say that the name StruBE stemms from Prof. Arold’s first hamster (R.I.P. 1981), but this has not yet been confirmed.

Research Interests

​Structural biology, cellular signalling, functional annotation, protein engineering

Selected Publications


  • 2004 Habilitation. University of Montpellier I, France
  • 1998 PhD degree 'European Label' (passed with distinction 'cum laude'). University of Montpellier I, France
  • 1995 D.E.A. (5th year of studies) in Molecular Biophysics and Molecular Biology (ranked major of group). University of  Montpellier I, France
  • 1994 Master degree (4th year of studies) in Physics. Joseph Fourier University, Grenoble, France
  • 1992 Vordiplom (second year diploma) in Physics, passed with best distinction ("sehr gut"). Unviversity of Würzburg, Germany 

Professional Profile

  • ​2013 – date Associate Professor of Bioscience, KAUST, Saudi Arabia
  • 2009 – 2013 Sabbatical (faculty appointment), MD Anderson Cancer Center (MDACC), Houston, USA
  • 2006 – date Tenured Associate Professor (CR1) in the French governmental CNRS, Centre de Biochimie Structurale (CBS), Montpellier, France
  • 2001 – 2006 Tenured Assistant Professor (CR2) CNRS, CBS, Montpellier, France
  • 1998 - 2001 Postdoctoral fellow, Laboratory of Molecular Biophysics, Oxford, UK (Structural Biology, Biophysics, Biochemistry)

Scientific and Professional Membership

​● Biochemical Society